Pseudo-UTP, 100mM Solution Phosphoramidites for Diagnostics [5] Gruenke

[5] Gruenke

tetrabutylammonium fluoride (TBAF) and triethylamine trihydrofluoride (TEA·3HF))

Christopher CW Lo et al

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4 (2015): 4522

Pseudo-UTP, 100mM Solution Phosphoramidites for Diagnostics [5] GruenkePseudouridine 5 triphosphate (TP) is a naturally occurring, modified uridine nucleotide supplied for enzymatic incorporation into RNA during IVT using RNA polymerases such as T7 RNA polymerase. When incorporated into RNA, pseudouridine can reduce innate immune recognition compared with unmodified uridine and improve RNA stability and translational performance. The 100 mM disodium salt solution provides TP in a highly soluble, ready to use form